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Changes observed in aged mice (12-months-old) include an upregulation of genes associated with the immune response, and a decrease in genes associated with environment probing and interactions with the ECM (Grabert et al., 2016

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Whether there will be equal accessibility to gene therapy for individuals with SCD in the US or globally is a challenging question for healthcare providers to answer

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10.3233/jad-2005-8211 67 PetersenR