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We observed that both APR-017 and LCS3 reduced the viability of VRK2-KO cells, but not VRK2-WT cells (Fig

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By day 2 of the differentiation the cells should have transited through PS to DE, in accordance we observed a down-regulation of MIXL1, GSC, NODAL , and T levels, while markers of DE namely, FOXA2, SOX17, CER1, HHEX and GATA4 were significantly upregulated (see Fig

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