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Neuroreport 1997
Production of large amounts of proinflammatory cytokines and ROS hyperproduction cause NF- B activation, a central event in the inflammatory response and further production of inflammatory cytokines [34, 35, 38]
About 90% of patients experience a prodromal phase (63), that is characterized mainly by signs and symptoms of autonomic dysfunction such as pallor, sweating, lethargy, hot flashes and rarely temperature change and drooling (65)
