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Maso, L., Bang, I

In vivo , administration of a mutant GDF8 prodomain that is resistant to TLD cleavage increased muscle mass as GDF8 inhibitors do, but wild-type GDF8 prodomain does not inhibit in this manner

Translating clinical guidelines into practice: the effective and appropriate use of human growth hormone

This subsection will systematically elaborate on the principles, clinical practice, and prospects of strategies combining ADCs with different types of drugs, such as immune checkpoint inhibitors (ICIs), small molecule targeted drugs, traditional chemotherapy, and emerging cell therapies

It is administered through subcutaneous injection and has been found to be safe and effective in clinical trials