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Hepatology (Baltimore, Md) 2007;46(2):3807
doi: 10.1177/03009858211005537 98 Santana-CodinaN.ManciasJ
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In diabetes and obesity, accelerated formation of an enlarged necrotic core is likely instigated by defective macrophage insulin signaling (176) and saturated fatty acids (177,178), which are potent inducers of ER stress
Furthermore, results from genetic screening suggest that anti-ferroptotic strategies are highly cell type specific and often context dependent 9
