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Thus, use of anti-angiogenic drugs such as bevacizumab or anlotinib may reduce hypoxia through vascular normalization to enhance infiltration of immune cells in tumors

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Neurobiol Dis 138 Xian X, Pohlkamp T, Durakoglugil MS, Wong CH, Beck JK, Lane-Donovan C, Plattner F, Herz J (2018) Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimers disease

Without a strong myelin sheath, nerves are exposed and become damaged, which may even lead to nerve cell death

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