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See Li, M., & Pinkel, D

The updated 2018 diagnostic criteria for PCOS require the presence of at least two of the following three features: (1) oligo/anovulation, (2) clinical and/or biochemical hyperandrogenism, and (3) PCO identified by the presence of 20 antral follicles per ovary on transvaginal ultrasound, with or without increased ovarian volume

UK guidelines recommend monitoring clinical response and full blood count (typically at around 2 months) to ensure treatment adequacy, rather than routinely rechecking B12 levels after replacement has started

The Janus Rectal Cancer Trial is the largest clinical trial in the world for RC patients, and we are well-positioned to perform and continue parallel co-clinical trial work at both MSK and MDACC

We support patients in safely reaching a target BMI of around 22, after which we transition them to a maintenance dose of Mounjaroeither 5 mg, 10 mg, or 15 mg, depending on their clinical needs
