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Olive oil (Colavita, Rome, Italy) was used to prepare a CCM stock solution

Cytotoxicity resulting from the dysregulation of cellular calcium homeostasis is a significant concern for nanomaterials, given the crucial role of Ca 2+ in intercellular signaling

315 In hyperuricemia, purine-rich diets shift the microbiota toward uric acid producers (e.g., Clostridium spp.), overwhelming renal excretion and triggering crystal formation and fibrosiseffects countered by probiotics such as Lactobacillus rhamnosus, which restore SCFA levels and barrier function

Supplementing with vitamin B12 lowers homocysteine levels and may improve mood, particularly in response to stress

The previously mentioned structures in the LAB cell wall are capable of the chelation of metal ions (Figure 2