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Although this Ni-loaded carrier allowed an in tandem purification and immobilization of enzymes directly from the cell lysate, the synthesis of carrier was rather complicated with a protocol of at least five steps, including the synthesis of mesoporous silica nanoparticles and grafting NiNTA, which may not enhance sustainability and cost effectiveness 29

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In a study comparing 13 dietary interventions in ASD, it was found that the Feingold diet did not have any side effect and ranked first in six areas related to behavior, including aggression, sensory sensitivity, hyperactivity, irritability, falling asleep and staying asleep, anxiety, attention, and sleep