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3 Methodology A modified Delphi exercise was conducted to achieve expert consensus
Calcium signaling Ca, a ubiquitous intracellular second messenger, is primarily stored in the endoplasmic/sarcoplasmic reticulum and mitochondria, where it plays a critical role in regulating pancreatic fluid and enzyme secretion

doi: 10.1254/jphs.95.19

For example, a large analysis of subjects from the Nurses Health Study and other studies found that diabetic subjects who carried the C allele of the GLUL gene were more likely to have coronary heart disease