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Recent clinical trials on older adults have demonstrated that 5-HTP supplementation significantly reduces sleep latency, helping patients fall asleep faster and achieve better overall sleep quality
( ( ( ( ( After review of the information provided by the applicant, we have the following concerns regarding whether SER-109 meets the substantial clinical improvement criterion

Table 3) and HOMA-IR (Fig 2A), but not serum glucose (Table 3)

Intrahepatic CPSS generally has poorer prognosis

Measurable changes in body composition typically become noticeable after 8 to 12 weeks of consistent use