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Lets look at some common factors that lead to carnitine deficiency in adults: Causes of deficiency Inadequate Carnitine Intake due to unbalanced meals, excessive junk food, or fad diets Lack Of Enzymes that are necessary for the metabolism of carnitine Hereditary Disorder is characterized by renal leakage of carnitine through the tubes Decreased production due to some liver disorder Loss of Carnitine due to gastrointestinal disturbance such as diarrhea, diuresis, or hemodialysis Mitochondrial impairment leads to low carnitine levels in muscles Deficiency symptoms L Carnitine deficiency can lead to various signs and symptoms due to its vital role in energy metabolism

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Another meta-analysis of trials that compared the safety profile of antidepressants found evidence of fewer adverse effects, and consequently, better adherence to treatment with ALCAR compared to placebo and in contrast to classical pharmaceutical agents (96)

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Am J Physiol Endocrinol Metab (2018) 315:E5119