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This absence of stringent oversight increases the risk of inconsistent product quality and potential safety issues

doi: 10.1016/j.fochx.2022.100479 49

[DOI] [PubMed] [Google Scholar] 64.Sakurai T, Hajiro K, Takakuwa H, Nishio A, Aihara M, Chiba T
Indeed, human origin spheroids might represent an up-grade level of conventional 2D cell culture

The absence of an identifiable cause does not mean the lesion is suspicious
