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Moreover, reports are inconsistent, indicating that BMIs, fasting insulin, and free testosterone levels decreased in some meta-analyses, but in other studies, there were no substantial changes in BMI or insulin resistance

Teunissen CE, Killestein J, Kragt JJ, Polman CH, Dijkstra CD, Blom HJ (2008) Serum homocysteine levels in relation to clinical progression in multiple sclerosis

5-fluorouracil: mechanisms of action and clinical strategies
