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10.3389/fimmu.2021.720363 Front Immunol

Male Mc4r- KO mice were kept on a HFHS diet for 9 weeks and the mice were 17 weeks old at study start (The Jackson Laboratory, 032518)
doi: 10.1186/s13742-015-0084-3 103 KangDWIlhanZEIsernNGHoytDWHowsmonDPShafferMet al

These findings highlighted the importance of host factors such as granuloma structure and immune environment in determining the efficacy of JAK blockers [14]

Roger John Williams founded the CFBI
