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Tryptophan is required for T cell function because its metabolism controls the immune system by serving as an immunomodulator [63]

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9.4 GSH-mediated immunotherapy Cancer immunotherapies, such as vaccines and immune checkpoint inhibitors, are most effective when their activity is confined to tumor sites

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Navarro-Alarcon, M., de la Serrana, H

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The first step is to modify the chemotherapy regimen, such as dose reduction and longer interval between cycles, especially platinum agents like oxaliplatin or cisplatin and vincristine [63]

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