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Description
Upon sensing environmental stress or cellular damage, the absent in melanoma 2 inflammasome (AIM2) and NLR family pyrin domain-containing 3 (NLRP3) inflammasome assemble and recruit the inflammasome adapter protein apoptosis-associated speck-like protein containing CARD, leading to the activation of pro-inflammatory caspases [137]
Frias, S
Julvez, J
Among the cytokines identified as being dysregulated by obesogens, IL-6 has been the most extensively studied in the context of PCa [359]
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