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Symptoms of B12 deficiency B12 deficiency produces symptoms that overlap frustratingly with common tirzepatide side effects : Fatigue and low energy : Often attributed to reduced caloric intake Brain fog and poor concentration : Mistaken for a dietary side effect Mood changes : Depression, irritability, anxiety Tingling in hands or feet : Peripheral neuropathy from B12 depletion Weakness : Often blamed on muscle-related side effects Because these symptoms mirror common GLP-1 side effects, B12 deficiency often goes unrecognized in people taking tirzepatide

In addition, it exhibits anti-inflammatory, anti-aging, wound-healing, skin-brightening, and anticancer effects, making it a promising therapeutic agent in dermatology [69]

[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Zhao Z., Koeplinger K.A., Padbury G.E., Hauer M.J., Bundy G.L., Banitt L.S., Schwartz T.M., Zimmermann D.C., Harbach P.R., Mayo J.K