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K(+) efflux is the common trigger of nlrp3 inflammasome activation by bacterial toxins and particulate matter

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CrossRef Targeting ERS-mitophagy in hippocampal neurons to explore the improvement of memory by tea polyphenols in aged type 2 diabetic rats Wenjuan Feng, Chenhui Lv, Le Cheng, Xin Song, Xuemin Li, Haoran Xie, Shuangzhi Chen, Xi Wang, Lushan Xue, Cheng Zhang, Jie Kou, Lili Wang, Haifeng Zhao Free Radical Biology and Medicine.2024

The inflammasome is a multiprotein complex that regulates inflammation by activating specific proinflammatory cytokines, resulting in an effective host immune response 74

In the present study, MDA increased oxytocin levels at least as much as MDMA and produced comparable effects on the VAS ratings of trust, feeling close to others, open, and talkative. These findings indicate that MDA may share certain prosocial effects with MDMA that could be of potential interest for substance-assisted therapy
