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After reviewing the evidence and guidelines for the diagnosis, screening, and management of familial hypercholesterolaemia, consensus was reached on the following aspects: clinical features, diagnostic criteria, screening in adults, screening in children, management in relation to target plasma low-density lipoprotein cholesterol levels, detection of atherosclerosis, lifestyle and behaviour modification, and pharmacotherapy

However, recruitment of HCV core protein from lipid droplets to the ER assembly site was independent of the ion channel activity of HCV p7 (Boson et al., Regulation of Host Lipid Metabolism by the Core Protein The mechanisms by which the core protein can induce liver diseases and extrahepatic manifestations are unknown

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