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In addition, dysregulated -KG flux from normal reductive anabolism via the TCA cycle toward R-2-HG production has been associated with other metabolic flux impairments and disrupted redox balance 119,120 (Fig

It is a different molecule with a different route of administration (subcutaneous injection) and was tested in Alzheimer's patients

Limitations of the Research Despite promising animal studies, key limitations remain: Human studies are sparse: Most research is conducted in rodents with few clinical trials

[121] [123] Malabsorption [edit] Individuals with pernicious anemia do not have the ability to produce intrinsic factor