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Mixing: Never shake the vial
Maintain an Active Lifestyle Regular physical activity is important for maintaining a healthy metabolism, which in turn supports the absorption and utilization of nutrients, including B12
The second trial used six weekly instillations and reported that 47% of patients administered DMSO (retention interval not specified) reported improvement compared to 0% of a BCG (two hour retention) instillation group at three months

However, a formal diagnosis can only be made by a healthcare professional