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In peripheral blood, CF patients consistently exhibit altered GSH status: reduced intracellular levels in neutrophils and lymphocytes (Lands et al., 1999

They are also essential for maintaining healthy mitochondria as damaged or malfunctioning mitochondria are part of the cancer process

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[DOI] [PMC free article] [PubMed] [Google Scholar] 662

These drugs inhibit cell cycle progression at G1/S checkpoint and exhibit significant improvement in progression-free survival and overall survival (in some cases) when combined with endocrine therapy (218)
