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These picomolar levels of 15-HpETE-PE alone (Supplemental Figure 4A, generated under IL-13 plus arachidonic acid conditions) would be insufficient to directly oxidize the nanomolar changes caused by oxidation of GSH to GSSG observed in response to IL-13 (or the change with inhibition of 15LO1 or KD of ALOX15 /15LO1)

Dos Santos, W.G., Pacheco, I., Liu, M.Y., Teixeira, M., Xavier, A.V., and LeGall, J., J

2024;19(9):e0297702 Ruiz-Baena JM

[DOI] [PubMed] [Google Scholar] 100.Laverde C.F., Morais-Silva G., Amaral V.C.S., Marin M.T

Amygdalin Inhibits TGF1-Induced Activation of Hepatic Stellate Cells (HSCs) In Vitro and CCl4-Induced Hepatic Fibrosis in Rats In Vivo