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The symptoms are more common at the start of treatment

Kim, J.Y., et al.,Osteoprotegerin causes apoptosis of endothelial progenitor cells by induction of oxidative stress.Arthritis Rheum, 2013

doi: 10.3389/fimmu.2022.864838

Ammonia enters lysosomes via the RHCG transporter, disrupting membrane structures and activating a cascade of cellular damage [87]

Guo X, Zuo X, Zhou Z et al (2023) PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases
