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H.FujimuraT.et al (2005)
M.RochaC
Hypoxic preconditioning promotes the bioactivities of mesenchymal stem cells via the HIF-1-GRP78-Akt Axis
In cell proliferation assays, DES(1-3) IGF-1 is approximately 10-fold more potent than native IGF-1, but IGF-1 LR3 achieves even greater sustained activation because its prolonged presence continuously stimulates the receptor
The reduced norepinephrine release may be beneficial also in other conditions with sympathetic hyperactivity such as heart failure and myocardial infarction in addition to the sparing effect of 1 -blockers on cardiac work load and energy consumption
