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Cisplatin: mode of cytotoxic action and molecular basis of resistance

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Obese women, however, experience inappropriately increased lipid peroxide levels and limited progression of endothelial function during their pregnancies, along with an additive innate tendency for central fat storage

Wang I-M, Stepaniants S, Boie Y, Mortimer JR, Kennedy B, Elliott M, Hayashi S, Loy L, Coulter S, Cervino S, Harris J, Thornton M, Raubertas R, Roberts C, Hogg JC, Crackower M, O'Neill G, Par PD: Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer

The prolonged half-life of GLP-1 analogs is achieved through several mechanisms, such as delayed absorption from the subcutaneous injection site, albumin binding, which shields the molecule from enzymatic degradation by DPP-4, and reduced renal clearance