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Description
Weight loss : Both can lead to weight loss as a secondary benefit
10.3389/fphar.2021.817236 20 BonnetA.MoreauP
CD44 signaling activates oxidative stress pathways, induces HIF1-driven metabolic shifts under hypoxia, and promotes epithelial-mesenchymal transition (EMT), a process in which epithelial cells lose polarity and cell-cell adhesion while acquiring mesenchymal traits, leading to increased motility and invasiveness
Furthermore, in this context Mller cells release ROS and prostaglandin E2 that also contribute to the apoptosis of RGCs (Gao et al., 2013
Nat Prod Commun 14:
