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However, according to the NIH, these studies also listed limitations that could have impacted their results [4]

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We computed directed simplices, a type of all-to-all connected clique, using algebraic topology (47, 48) to quantify the topological complexity of the network (see Methods )

In this study, 56 participants (29 patients in the experimental group and 27 patients in the control group) received classical sinusitis treatment with either 3% normal saline or 3% normal saline plus 6% N-acetyl cysteine

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