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Persons affected by major depressive disorder manifested acetyl-l-carnitine deficiency compared to age- and sex-matched healthy individuals in two independent study centres

L-acetylcarnitine: a proposed therapeutic agent for painful peripheral neuropathies

On the contrary, these metabolites were not produced by the rats receiving the isotope intravenously and germ-free rats receiving the tracer orally, suggesting that orally ingested LC is in part degraded by the guts microorganisms [55]

J Physiol-London

[DOI] [PubMed] [Google Scholar] 73.Hoffmann GF, Athanassopoulos S, Burlina AB, Duran M, de Klerk JB, Lehnert W, Leonard JV, Monavari AA, Muller E, Muntau AC, Naughten ER, Plecko-Starting B, Superti-Furga A, Zschocke J, Christensen E