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Globisch D, Mnzel M, Mller M, Michalakis S, Wagner M, Koch S, Brckl T, Biel M, Carell T (2010) Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

10.1038/s41586-023-06328-6
So, it could be that an ultrasound scan would be needed to try and diagnose that problem
Organ-on-a-chip in vitro models of the brain and the blood-brain barrier and their value to study the microbiota-gut-brain axis in neurodegeneration

The severity of these reactions led to an 18% discontinuation rate in the clinical trial, indicating that nearly one in five patients cannot tolerate the treatment protocol