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Challenging the dogma of varied and multisystem involvement in mitochondrial disease, mutations in MT - ATP6 and MT - ATP8 have recently been shown to cause less severe phenotypes, including recurrent attacks of symmetrical limb paralysis and a later-onset distal motor neuropathy, mimicking periodic paralysis due to channelopathies [51, 52]

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Timely use of the LRT, at the earliest signs of toxicity, can improve resuscitative efforts and decrease the amount of vasopressors used

Support vector machines (SVMs) were used for the ROC curve analysis