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Description

Combined treatment with L-Carnitine and nicotinamide riboside improves hepatic metabolism and attenuates obesity and liver steatosis

Because the heart muscle derives the vast majority of its energy from the beta-oxidation of fatty acids, a depletion of L-Carnitine severely compromises the heart's ability to sustain this compensatory effort

W.Di ZazzoA.De GregorioC.NarangP.JhanjiV.BasuS

This review provides an overview of the complex network of carnitine synthesis, transport, shuttle, and regulation, carnitine/acylcarnitines have the potential to be used as communication molecules, biomarkers and therapeutic targets for multiple diseases, with profound effects on intercellular communication, metabolic interactions between organs and overall metabolic health