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doi: 10.1016/j.humpath.2017.12.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 119.Khan KN, Fujishita A, Koshiba A, et al

Samples were allowed to cool, and 1.375 ml purified water with a resistivity 18.2 M cm from a Milli-Q system (Merck Millipore) was added to make up to a final volume of 1.5 ml

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The extensive R-domain and NBD1 interactions increase the ATPase rate in a manner consistent with CFTR, where R-domain phosphorylation potentiates ATP binding and hydrolysis but otherwise does not induce transport activity alone 34

Animal studies show NAC protects against pulmonary inflammation, edema, MPO activity, cellular infiltration, and cytokine elevation (TNF-, IL-6, IL-1, CXCL10) in swine influenzainduced lung injury (129)