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However, it is contraindicated in patients with chronic liver failure due to concerns about hepatic encephalopathy and associated symptoms like malaise, nausea, appetite loss, and abdominal cramps (23)

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254 Another meta-analysis that included data from 371 NAFLD patients participating in five randomized controlled trials found liraglutide significantly reduced BMI, especially in those with co-occurring type 2 diabetes, but its lowering effects on liver fat and ALT levels were not statistically significant

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