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An alternate strategy could be to use redesigned methionine analogs, such as ethionine

(PubMed) Tangney CC, Tang Y, Evans DA, Morris MC

Elevation of ROS levels results in oxidative stress in airway epithelial cells which activates an antioxidant defence mechanism known as the Keap1Nrf2 pathway to counteract the harmful effects of oxidative stress (Schieber and Chandel 2014)

The compounds showing up in those videos are not Ozempic, a different peptide altogether, built and tested through a completely different process

For generating point mutations in both plasmids, we used a modified version of the quikchange protocol