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In this respect, an interesting study conducted on immortalized human microglia cells (CVCL_5G94) highlighted how ATRAs can increase the heat shock protein 90 (Hsp90) expression on the surface of these cells, causing an increase in the amount of endocytosed and consequently eliminated tau protein (25)

Changes in the pentose phosphate pathway in HF The regulation of the cellular redox environment is tightly linked to substrate metabolism via the PPP as an important source of NADPH

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Boam, Esq
