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Eukaryot Cell 1:391400 Sohn MJ, Yoo SJ, Oh DB, Kwon O, Lee SY, Sibirny AA, Kang HA (2014) Novel cysteine-centered sulfur metabolic pathway in the thermotolerant methylotrophic yeast Hansenula polymorpha
The antioxidant response genes activated by NRF2 include genes responsible for (a) regulating GSH synthesis and metabolism, (b) antioxidant proteins like GPX, (c) drug-metabolizing enzymes and xenobiotic transporters, and (d) additional stress response proteins (Jaramillo and Zhang, 2013)
And an H2A deubiquitinase, tumor suppressor BAP1-mediated SLC7A11 inhibition, does not require Nrf2 and ATF4 transcription factors but represses SLC7A11 expression by reducing H2A ubiquitination (H2Aub) on the SLC7A11 promoter (Zhang et al., 2019)
Reversible inactivation by hydrogen peroxide
Biochem J 474:24352447 Bates LS, Waldren RP, Teare ID (1973) Rapid determination of the free proline for water stress studies
