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Noncontrast brain CT showed mild brain atrophy with chronic small vascular disease

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Following intravenous injection, LrD primarily accumulated in the liver, with comparatively lower levels in all other tissues, and the lowest concentration was observed within the tumors (Supplementary Fig

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Residues Phe40, Leu43 and Phe47 from Syt1 form hydrophobic interactions with several hydrophobic amino acids in the nanobody, including Val34, Tyr46, Trp59, and Trp108