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The Power of Glutathione Glutathione, often heralded as the body's 'master antioxidant,' is a tripeptide composed of three amino acids: cysteine, glutamate, and glycine

However, cysteine depletion generally induces stronger ferroptotic responses compared to GSH depletion 10 , which is suggestive of additional mechanisms underlying cysteine starvation-induced ferroptosis

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As such, it is apparent that additional experimentation focusing on genomics, environmental/nutritional components and their crosstalk is warranted to determine the causal factor(s) that reduce both cystine and selenoprotein levels in children affected with konzo to unravel the biological mechanism behind this disease

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