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Dhillon, 2018), while trials of IDH inhibitors for other tumors such as cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndrome are still underway (Abou-Alfa et al., 2020

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Therefore, this protein can be considered one of the players in accomplishing metabolic needs of cancer cells and, hence, a druggable target (Figure 1B)

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