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Methotrexate-induced hepatotoxicity-mechanism, clinical cases and treatment approaches

In laboratory environments, it is frequently explored in peptide signalling and molecular interaction studies

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The risk of anti-tuberculosis drug induced hepatotoxicity has been found to increase by various factors like high alcohol intake, older age, pre-existing chronic liver disease, chronic viral infection, advanced TB, female sex, concominant administration of hepatotoxic drugs, inappropriate use of drugs and nutritional status [19,130]
