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Description
25,26 Introduction of an amino substitution at the C 3 position of the methylated analogs of isoquinoline yielded 2 , displaying an IC 50 value of 6.3 2.7 M
In aging research, the compound provides a unique approach to investigating theories of metabolic decline, as NNMT expression increases with age in many tissues, potentially contributing to the NAD+ decline associated with aging processes
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A., Taher, I., Abubaker, J