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Consistent with a role of the Leu allele in lung cancer risk, a casecontrol study of lung cancer from Korea found that individuals with at least one Leu allele had increased levels of urinary 8-hydroxydeoxyguanosine, the mutagenized DNA oxidation product compared to Pro/Pro (211), as well as a greater risk for lung cancer

References: Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D

Silencing of GAS5 alleviates glaucoma in rat models by reducing retinal ganglion cell apoptosis

10.3390/ijerph192316310 65 ShuiX.ChenJ.FuZ.ZhuH.TaoH.LiZ.et al

Tajan M, Hock AK, Blagih J, Robertson NA, Labuschagne CF, Kruiswijk F, et al