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IMAC is applicable to proteins with a broad range of physiochemical properties and structural variations

However, growing evidence shows that in ME/CFS, this energy-production system is severely impaired

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Chen Z., Zhong C

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An increased activity of estrogen receptors (ERs), a local estrogen production in endometriotic cells, and a progesterone receptor decreased activity (progesterone-resistance) are considered the main causes of impaired apoptosis, reduced immune function, and increased inflammation [18]