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We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig

Under oxidative stress, the GSH/GSSG ratio ranges from 5:1 to 1:1 28

These data support an NRF2-dependent effect of DMF on CBS expression regulation

10.1038/s41467-024-47686-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 51.Rubio-Navarro A, Gomez-Banoy N, Stoll L et al (2023) A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes

[abgerufen am 24.01.2024] Helms, F