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Description
ABBV-399 targets the SEMA domain of c-MET, blocking HGF binding and inducing receptor internalization, degradation, or cytotoxic effects [10]

Furthermore, a cross-sectional study has demonstrated that higher levels of mineral metabolism and fibroblast growth factor 23 (FGF-23), which have been correlated with adverse cardiovascular events and death (61) in patients receiving hemodialysis are independently associated with worse memory scores in comprehensive neurocognitive tests (62)

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Pain behavior was quantified periodically in phases 1 and 2 by counting the number of flinches in the ipsilateral paw after injection with 30 L of 5% formalin

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