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Labeled HT-29 cells were pretreated with PBS, PV2, ncAA-nanobody, PV2-PV3 fusion nanobodies and Durvalumab served as positive controls and seeded onto 12-well culture plate at 2 10 5 cells per well (macrophage tumor cell ratio: 1:4)

Serving as effector cells in the innate immune response, these cells represent the most abundant type of immune cells among human white blood cells