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Where the evidence was convincing, we changed what we do
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In addition to its direct antitumor effects, daratumumab exerts an indirect immunomodulatory role by eliminating CD38 + immunosuppressive cell types (Treg, Breg and myeloid-derived suppressor cells) in the tumor microenvironment (TME), thereby promoting T-cell proliferation and effector functions [44]
Some patients report a warm or flushing sensation immediately following injection, which is normal
The peptide is supplied with high purity to support reproducible results in experimental investigations
