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The exact pathways through which T cell proliferation is inhibited by IDO in vivo are not fully understood

24-hour metabolic rate in insomniacs and matched normal sleepers

CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion

Consequently, iron chelators are more effective in counteracting its effects than they are against other substances

Given the limitations of current single-target therapies, interest has grown in natural products as promising multi-target agents for modulating AD pathology (Zhang et al., 2024)